CAS No.: | 1159861-00-3 |
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Formula: | / |
EINECS: | / |
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GMP Lab Tirze500 Dsip PE-22-28 Pnc-27 Fox 04-Dri Ll37 B7-33 Kisspetin-10 Gdf-8 Acetate Ss-31 Thymosin Tb 2mg 5mg 10mg 15mg Raw material powder
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Product Name: | PNC-27 | Cas No. | 1159861-00-3 |
Purity: | 99% | Formula weight: | 0 |
Package: | Foil Bag | Molecular formula: | 0 |
MOQ: | 1 Gram or 1 Box | EINECS: | 0 |
Transportation: | By Air | Grade Standard | Top Quality |
Sample | Availiable | Shelf Life | 2 Years |
Description:
Anti-cancer peptide, PNC-27, is a membrane-active peptide that binds to the HDM-2 protein expressed in the cancer cell membranes of solid tissue tumor cells. The peptide induces transmembrane pore formation in cancer, but not in normal cells, resulting in tumor cell necrosis (cell death).
PNC proteins were first theorized and created in 2000 by Drs. Matthew Pincus and Joseph Michl at the SUNY Downstate Medical Center in New York. Although they were originally intended to combat HIV, PNC-27 showed a remarkable ability to bind to cancer cells, causing them to die, while leaving healthy cells undamaged.
The PNC-27 cancer peptide is a nontoxic compound that causes the death of cancer cells only, leaving all other healthy cells unaffected. It is able to do this by attaching to the membranes of the individual cancer cells, creating holes in those membranes. As a result of the holes, rapid implosion occurs, leading to swift cell death due to the osmotic pressure difference in the inside vs. outside of the tumor cells.
PNC-27 accomplishes this due to its affinity for binding to a protein called HDM-2. Cancer cells have HDM-2 in their cell membranes. When the PNC-27 peptide is administered, it immediately travels to the HDM-2 located in the membranes of cancerous cells. By binding to them, it creates pores or holes in the cell membrane, causing membranolysis,; or death of the cell membrane.
Measure |
CagriSema |
|
Cagrilinitide |
Number of participants |
31 |
31 |
30 |
Average decrease in A1C |
2.2% |
1.8% |
0.9% |
Percentage of participants with an A1C ≤ 6.5% |
75% |
48% |
17% |
Average decrease in body weight |
15.6% |
5.1% |
8.1% |
Average increase in time in range |
43% | 43.6% | 14.8% |
Henan tirzepa new material Co., LTD in China.Our company is mainly engaged in chemical organic raw materials, peptides ,raw oil, we have been engaged in this industry for 8 years. Our products are very rich, we have a professional R & D and production team. Our products are of high quality, inexpensive and customizable.
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Q: Can I get free samples? |
A: Sure, we can provide a free sample, but the shipping cost will be paid by the customers. |
Q: How to make payment? |
A: Payment via Western Union, Money Gram, Bank Account Wise and Bitcoin are acceptable. |
Q: How to delivery? |
A: Parcel will be shipped out in 2 workdays after payment, usually via FedEx, EMS, HKEMS, DHL, TNT, USPS Domestic fast shipping, signature not requested. |
Q: Is there any discount? |
A: Yes.The price is negotiable, just send us the quantity of items you need, we will apply you the best price and discount. |
Q: What is the Minimum order quantity? |
A: peptide minimum is 1 box, powder is 50g. some expensive items is 10g 5g. |